SHOPPING CART
Your cart is empty.
shop now
Many labs struggle to keep volatile samples safe and stable during DSC analysis. Leaks, rapid evaporation, and signal loss can make data unreliable.
Choosing the right PerkinElmer DSC sample pan for volatile samples helps prevent leaks and controls evaporation. Using pans designed for volatile substances improves the safety and accuracy of thermal analysis results.
Through my experience in research, I know that working with volatile materials brings challenges that standard pans cannot handle. I have seen tests fail from unnoticed leaks or open seals. Using a step-by-step approach to pan selection and prep makes every run safer and more successful.
What are the challenges of analyzing volatile samples in DSC?
Fast evaporation or chemical breakdown can quickly ruin DSC tests with volatile samples. Labs must manage leaks and unexpected reactions at every step.
The main challenges include controlling evaporation, preventing leaks, and protecting the sample from contamination and pressure buildup during the thermal cycling process.
| Challenge | Impact | Advice/Reference |
|---|---|---|
| Evaporation | Results in sample loss and incorrect heat flow measurement | Use hermetic sealing or quick crimp sealing |
| Leaks | Leads to contamination and messes the DSC instrument | Check for perfect pan rim and fit of the lid |
| Pressure Build-Up | High pressure can cause pan rupture or data errors | Choose vented or high-pressure compatible pans as needed |
| Contamination | Ruins baselines, distorts results | Work in a clean area and use new pans every time (sample preparation) |
A few years ago, my team lost several rare chemical samples to evaporation before the run finished. After switching to better sealed pans and cleaning standards, those losses dropped to almost zero.
Which PerkinElmer DSC sample pans are suitable for volatile samples?
Standard open pans often lose material fast when handling liquids or volatile solids. Choosing the right pan type is key for all thermal analyses with volatile samples.
For volatile samples, sealed (hermetically crimped) or vented PerkinElmer DSC pans are best. They prevent leaks, minimize evaporation, and some can manage slight pressure changes.
| Pan Type | Best For | Key Features/Reference |
|---|---|---|
| Hermetic Sealed | Liquids and sensitive volatile solids | Aluminum body, hermetic closure, prevents escape of sample and vapor |
| Vented | Samples that may release gas under heat | Small vent hole allows controlled pressure release, prevents rupture |
| High Pressure | Pressurized tests of highly volatile or reactive materials | Special construction, supports greater internal pressure, more costly |
I choose hermetic sealed pans for alcohol mixes and vented pans for adhesives or samples that bubble. For rare or regulated samples, I also ask suppliers for technical data on pressure handling before ordering a new pan type.
How to prepare volatile samples for DSC analysis?
Many mistakes happen during sample loading and sealing, especially with fast-evaporating liquids. Handling technique makes as big a difference as the pan type itself.
To prepare volatile samples, load quickly in a cool, draft-free room, seal pans right after loading, and use tools cleaned of oil, dust, or moisture. Keep everything ready before opening the sample vial.
| Step | Purpose | Tips/Reference |
|---|---|---|
| Chill Sample if Needed | Reduces evaporation loss during loading | Work below room temperature for volatile substances |
| Pre-Weigh Pans | Lets you measure true sample mass | Weigh quickly using an analytical balance |
| Handle with Clean Tools | Prevents contamination that distorts results | Gloves and metal tweezers work best |
| Seal Immediately | Minimizes exposure and evaporation | Organize seals and pans before you start loading |
One summer, I handled a volatile monomer sample. Setting the workspace to 15°C and sealing pans within seconds of weighing made my recovery rates almost perfect, compared to many failed attempts at room temperature.
What precautions should be taken when analyzing volatile samples?
Ignoring safety with volatiles can cause spills, pressure blowouts, or ruined equipment. Only clear lab routines and the right gear protect data and people.
Always use a fume hood, wear proper PPE, and do small-scale trial runs first. Confirm pan seals and monitor for pressure changes during every experiment.
| Precaution | Purpose | Advice/Reference |
|---|---|---|
| Work in Fume Hood | Protects from vapors and accidental leaks | Follow institutional chemical safety measures (fume hood) |
| Wear PPE | Guards skin and eyes from spills and splashes | Minimum: gloves, goggles, lab coat |
| Trial Run | Tests both sample and pan seal before real measurement | Look for leaks, pan swelling or unexpected pressure |
| Monitor Experiment | Catches issues early, lets you stop test safely | Watch for sudden changes in baseline or instrument noise |
I always set up a test run with water or alcohol first, to confirm pan integrity and instrument behavior. This habit prevents big problems in busy production periods.
Choosing the right DSC pan and safety steps protects volatile samples and gives trustworthy data. Preparations, sealing technique, and personal safety all matter from start to finish.
Contact Us: info@redthermo.com
